Glucosamine HCL Information
We have known for quite a while that our customers using our KODA Proflexoil for their dogs have noted a reduction in pain and symptoms for joint problems. Below are the results of a NIH study that confirms in trials that using this natural combination appears to be as effective as NSAID’s like Celebrex. We have been against Vet’s prescribing NSAID’s, but have not had the research trials to be able to offer factual results. Even though this study is for humans, the biological systems of dogs and humans are very similar because of their millennial symbiosis. We are happy to read this study as it confirms our own observations.
Chondroitin sulfate plus glucosamine works just as well to ease the symptoms of knee osteoarthritis as anti-inflammatory drugs, according to study results published in the journal Annals of the Rheumatic Diseases.
Osteoarthritis is the most common form of arthritis in the Western world, and the knee is the joint that gets hit with it most frequently. Osteoarthritis is expected to become the fourth leading cause of disability by 2020, write the study’s authors.
Because the non-steroidal, anti-inflammatory drugs (NSAIDS) often used for arthritis can themselves cause serious gastrointestinal and cardiovascular effects, scientists have been hunting for alternatives for years.
The recently completed trial, called the MOVES trial (Multicentre Osteoarthritis InterVEntion trial with Sysadoa) was conducted in Europe among a group of 606 patients with primary knee osteoarthritis and moderate to severe pain who were recruited from 42 centers in Spain, Germany, France and Poland. A multidisciplinary team of investigators including rheumatologists, orthopaedists and primary care physicians participated. In the double-blind, randomized, multicenter, parallel group trial, patients were given pharmaceutical grade chondroitin sulfate (1200 mg/day) and glucosamine hydrochloride (1500 mg/ day) or 200 mg of celecoxib (an anti-inflammatory drug) daily for six months.